BDBM144315 Gilteritinib::US11512074, Example T-9::US8969336, 547::US8969336, 577

SMILES CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(CC3)N3CCN(C)CC3)c(OC)c2)nc1NC1CCOCC1

InChI Key InChIKey=GYQYAJJFPNQOOW-UHFFFAOYSA-N

Data  5 KI  37 IC50

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 144315   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Astellas Pharma

US Patent

LigandBDBM144315(Gilteritinib | US11512074, Example T-9 | US8969336...)Copy SMILESCopy InChI

Affinity DataIC50:  3.40nMAssay Description:A partial protein of only a kinase domain of RET protein was purchased from Carna Biosciences Inc., Japan. The phosphorylation activity toward a pept...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
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Ligand InfoPurchaseMCE
PC cidPC sidPDBSimilars

In DepthDetails US Patent
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